
L-theanine is an amino acid found abundantly in tea leaves, especially green tea. A 2008 study by Nobre et al. indicates that L-theanine has properties that promote relaxation without causing drowsiness.
A 2010 study by Giesbrecht et al. showed that when consumed with caffeine, L-theanine helps increase alertness and ability to concentrate.
A 2019 study by Hidese et al. found that L-theanine helps reduce stress and anxiety symptoms in various situations.
Although not a sleeping pill, a 2011 study by Lyon et al. suggests that L-theanine can help improve sleep by reducing stress and anxiety.
Generally, the recommended amount of L-theanine is between 200-400 mg per day. L-theanine is considered highly safe with no severe side effects reported in short-term use.
Inositol is a sugar-like compound once classified as a B vitamin, but is no longer considered a vitamin as the body can produce it. A 2014 study by Bizzarri et al. states that Inositol plays a crucial role in cell function and the nervous system.

A 2012 study by Unfer et al. suggests that Inositol helps balance hormones and may help alleviate Polycystic Ovary Syndrome (PCOS).
A 2019 study by Pintaudi et al. shows that Inositol may increase insulin sensitivity, which could be highly beneficial for diabetic patients.
The amount of Inositol used in clinical studies ranges from 2-18 grams per day, depending on the purpose. Inositol is highly safe but may cause diarrhea or nausea if used in excessive amounts.
Both L-theanine and Inositol have stress and anxiety-reducing properties. Using them together may enhance their effects in alleviating these symptoms.
L-theanine helps improve sleep quality, while Inositol may reduce anxiety that can disturb sleep, thus making sleep more effective.
Both L-theanine and Inositol are nutrients beneficial to health. L-theanine has properties that reduce stress and increase focus, while Inositol plays a crucial role in hormone balance.
However, it's important to choose reliable, legal brands approved by the Thai FDA and certified by international standards for safety.
References
Nobre AC, Rao A, Owen GN. L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pac J Clin Nutr. 2008;17 Suppl 1:167-8.
Hidese S, Ogawa S, Ota M, et al. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients. 2019;11(10):2362.
Lyon MR, Kapoor MP, Juneja LR. The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial. Altern Med Rev. 2011;16(4):348-54.
Giesbrecht T, Rycroft JA, Rowson MJ, De Bruin EA. The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness. Nutr Neurosci. 2010;13(6):283-90.
Bizzarri M, Carlomagno G. Inositol: history of an effective therapy for Polycystic Ovary Syndrome. Eur Rev Med Pharmacol Sci. 2014;18(13):1896-903.
Unfer V, Carlomagno G, Dante G, Facchinetti F. Effects of myo-inositol in women with PCOS: a systematic review of randomized controlled trials. Gynecol Endocrinol. 2012;28(7):509-15.
Pintaudi B, Di Vieste G, Bonomo M. The Effectiveness of Myo-Inositol and D-Chiro Inositol Treatment in Type 2 Diabetes. Int J Endocrinol. 2016;2016:9132052.