
NADH (Nicotinamide Adenine Dinucleotide) and CoQ10 (Coenzyme Q10) are nutritional supplements that play important roles in cellular energy production. Taking both together can enhance their effectiveness and bring various health benefits.
NADH is a derivative of vitamin B3 that plays a crucial role in cellular energy production processes. NADH's main function is to transport electrons in the cell's energy production process and maintain energy levels so they don't become too low.
CoQ10 or Coenzyme Q10 is an antioxidant naturally produced by the body. It plays an important role in energy production within mitochondria, which are the cell's power plants, and also helps slow cellular degeneration.
According to Birkmayer's 2011 study, NADH and CoQ10 work together in the cell's energy production process. NADH provides electrons to CoQ10 in the electron transport chain, making ATP production (the cell's main energy source) more efficient.
Research by Ernster and Dallner in 1995 states that both NADH and CoQ10 have antioxidant properties, helping protect cells from damage caused by free radicals and reducing the risk of various chronic diseases.
Research by Mortensen et al. in 2014 indicates that CoQ10 plays an important role in heart muscle function, while NADH helps increase blood circulation. Taking them together may help reduce the risk of heart disease.
According to a 2015 study by Castro-Marrero et al., supplementing with both NADH and CoQ10 may help alleviate chronic fatigue, especially in patients with Chronic Fatigue Syndrome (CFS).
Research by Beal in 2004 states that NADH and CoQ10 play a role in protecting nerve cells and may help slow brain degeneration, reducing the risk of Alzheimer's and Parkinson's diseases.
A 2008 study by Cooke et al. suggests that supplementing with NADH and CoQ10 may help increase endurance and efficiency during exercise, especially for athletes who require high energy.
Taking NADH together with CoQ10 can provide various health benefits, especially in terms of increasing energy, fighting free radicals, and supporting heart and brain health. However, they should be taken in appropriate amounts. Choose products that meet standards, have international certifications, and are properly approved by Thailand's FDA to ensure authenticity and quality.
References
Birkmayer, J. G. D. (2011). Coenzyme nicotinamide adenine dinucleotide: New therapeutic approach for improving dementia of the Alzheimer type. Annals of Clinical & Laboratory Science, 41(1), 1-3.
Ernster, L., & Dallner, G. (1995). Biochemical, physiological and medical aspects of ubiquinone function. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1271(1), 195-204.
Mortensen, S. A., et al. (2014). The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: Results from Q-SYMBIO: A randomized double-blind trial. JACC: Heart Failure, 2(6), 641-649.
Castro-Marrero, J., et al. (2015). Does oral coenzyme Q10 plus NADH supplementation improve fatigue and biochemical parameters in chronic fatigue syndrome? Antioxidants & Redox Signaling, 22(8), 679-685.
Beal, M. F. (2004). Mitochondrial dysfunction and oxidative damage in Alzheimer's and Parkinson's diseases and coenzyme Q10 as a potential treatment. Journal of Bioenergetics and Biomembranes, 36(4), 381-386.
Cooke, M., et al. (2008). Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. Journal of the International Society of Sports Nutrition, 5(1), 8.